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Year:
2016 |
Month:
October
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Volume:
5 |
Issue:
4 |
Page:
PO22 - PO26 |
Study of Tuberculin Reactivity in Clinically Suspected Cases of Pulmonary Tuberculosis in Children & Adolescents
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Correspondence
Santhosh Jose, Mohamad Ismael K, Dr. Mohamad Ismael K
Assistant Professor, Department of Paediatrics,
MES Medical College, Perinthalmanna,
Kerala University of Health Sciences, Kerala, India.
E-mail: hensapapa@gmail.com :
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Introduction: India harbors highest number of tuberculosis (TB) patients globally. Few studies have focused on TB in young children who constitute a vulnerable population and lack of early diagnosis results in increased morbidity.
Aim: To study the tuberculin reactivity in clinically suspected cases of pulmonary tuberculosis in children and adolescents attending Paediatrics OPD in a tertiary care centre and to study the effect of nutritional status of children on tuberculin reactivity. Study design: Cross sectional study was conducted in Department of Pediatrics of MES Medical college Hospital, Perinthalmanna, for a period 1 year starting from 01/01/2013 to 31/12/2013. In all 1120 subjects were considered for the study out of which 111 patients lost follow-up hence a final sample size of 1009 was obtained.
Materials and Methods: Children aged between 1 to 18 years with suspected TB were prospectively enrolled at a Tertiary Hospital in Malappuram district, Kerala, India. Children were specifically examined for BCG scar. Tuberculin testing was done in all children using the purified protein derivative (PPD).
Results: Tuberculin reactivity among clinically suspected cases of Pulmonary tuberculosis using 1TU PPDRT23 was only 4.8 % as per our study which is in concordance with new sputum positive /case detection rate in Malappuram district, ie; 22-25 per lakh per year. Malnourished children had more tuberculin reactivity than normal children in our study.
Conclusion: Tuberculin test has a sensitivity only of 4.8% among all clinically suspected cases of tuberculosis, and malnutrition and tuberculosis often co-exist and worsen each other.
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